Covid-19 and vulnerability As Covid-19 impacts millions of people across the world, the most vulnerable will be affected most acutely, and the impact on them will be felt the longest. In many low-income countries, girls in particular face multi-dimensional challenges. We know that out of school, many will face great pressures related to increased household responsibilities and income-generating burdens, as well as increased risks of early marriage and pregnancy. Similarly, children with disabilities may be locked out of learning completely, with shifts to ‘remote’ learning unable to overcome the often-complex barriers to accessing material without appropriate content mediation. As systems begin to reintegrate, there is a real risk that many of the most vulnerable will not return to school. This generational impact of the Covid-19 crisis requires all our knowledge, expertise and endeavour to avoid.